In these patients it is recommended to perform serial echocardiography including 2 examinations in the first 3 weeks after onset  the treatment of choice is 30 mg/kg acetylsalicylic acid daily until the fever settles as well as intravenous immunoglobulins, 2 g/kg, as a single infusion within 10 days of onset. other infection control measures are of importance until REV7 the final diagnosis is established. strong class=”kwd-title” Keywords: Staphylococcal Scalded Skin Syndrome, dermatitis exfoliativa neonatorum, staphylogenic Lyell syndrome, Kawasaki syndrome, infection control measures Abstract Kindliche Exanthemata k?nnen durch ein breites Spektrum von Erregern verursacht werden. Oft pr?sentieren Bisoprolol sie sich anf?nglich ?hnlich, obwohl sie von unterschiedlichen Erregern wie Viren, Bakterien und deren Toxine verursacht werden k?nnen. Zumeist ist die Diagnose von akademischer Bedeutung, da sich die kausale Therapie kaum unterscheidet. In einigen F?llen ist jedoch eine genaue und rasche Diagnose von h?chster Bedeutung, da die korrekte Therapie und geeignete Hygienema?nahmen Morbidit?t und Mortalit?t verhindern. Wir pr?sentieren einen Fall mit zwei Differentialdiagnosen, Staphylococcal Scalded Skin Syndrome (SSSS) und Kawasaki-Syndrom (KS), der die Notwendigkeit der Differenzierung von seltenen kindlichen Krankheiten aufzeigt. Unterschiede im therapeutischen und hygienischen Management werden diskutiert. Von krankenhaushygienischer Bedeutung ist, dass SSSS im Gegensatz zu KS auf andere p?diatrische Patienten ber die H?nde der Mitarbeiter bertragbar ist. Daher sind korrekte H?ndehygiene sowie weitere hygienische Ma?nahmen dringend einzuhalten, bis die endgltige Diagnose vorliegt. Introduction Childhood exanthemata are caused by a broad spectrum of common pathogens. Many exanthemata initially present very similarly, even though caused by different organisms C ranging from virus to bacteria C as well as having different rates of morbidity and mortality. In the majority of cases the diagnosis is only of academic value, since therapy does hardly differ. However, in some cases accurate and prompt diagnosis is paramount, since therapy and appropriate hygiene measures prevent added morbidity and mortality. We present a case which demonstrates the importance of considering relatively rare conditions as the cause of a childhood exanthema. The one main differential diagnosis, Staphylococcal Scalded Skin Syndrome (SSSS), also known as dermatitis exfoliativa neonatorum or staphylogenic Lyell syndrome, is caused by group II coagulase-positive staphylococci, usually phage type 71, which elaborate exfoliatin (also called epidermolysin), a toxin that splits the upper part of the epidermis just beneath the granular cell layer . The infection often begins during the first few days of life in the umbilical stump or diaper area; in older children, the face is the typical site. Toxin produced in these areas enters the circulation Bisoprolol and affects the entire skin. The differential diagnosis includes drug hypersensitivity, viral Bisoprolol exanthemas, scarlet fever, thermal burns, genetic bullous diseases (e.g. some types of epidermolysis bullosa), acquired bullous diseases (e.g. pemphigus vulgaris, bullous pemphigoid), toxic epidermal necrolysis and rare the Kawasaki syndrome. Kawasaki syndrome (KS) or Kawasaki disease is an acute febrile illness of unknown etiology that primarily affects children younger than 5 years of age. KS is characterized by fever, rash, swelling of the hands and feet, irritation and redness of the whites of the eyes, swollen lymph glands in the neck, irritation and inflammation of the mouth, lips, and throat. Serious complications include coronary artery dilatations and aneurysms. The standard treatment with intravenous immunoglobulin and aspirin substantially decreases the development of these coronary artery abnormalities . For epidemiologic surveillance, CDC defines a case of KS as illness in a patient with fever of 5 or more days duration (or fever until the date of administration of intravenous immunoglobulin if it is given before the fifth day of fever), and the presence of at least 4 of the following 5 clinical signs : rash cervical lymphadenopathy (at least 1.5 cm in diameter) bilateral conjuctival injection oral mucosal changes peripheral extremity changes. Because SSSS is, in contrast to Kawasaki Syndrome, highly transmissible to other paediatric patients via the hands of the staff, isolation of cases is recommended, whereas for KS isolation of cases is not required. Case report A 15 month old boy Bisoprolol presented with generalised rash for two weeks, runny nose for one week and off feeds. No fever was noted by his mother. One day prior to admission the familys general practitioner prescribed 250 mg Flucloxacillin, 8 hourly, of which only one dose was taken. The patient was known to suffer from atopy. His asthma was.