Weidle, Matthew D
Weidle, Matthew D. McGuire, Frank DiMaio, Leonidas Stamatatos, Marie Pancera, David Veesler. 2018. Germline VRC01 antibody Ivachtin identification of the improved clade C HIV-1 envelope trimer, 2 Fabs destined, sharpened map. RSCB Proteins Data Loan provider. 6MZJAndrew J Borst, Connor E Weidle, Matthew D Grey, Brandon Frenz, Joost Snijder, M Gordon Joyce, Ivelin S Georgiev, Guillaume End up being Stewart-Jones, Peter D Kwong, Andrew T McGuire, Frank DiMaio, Leonidas Stamatatos, Marie Pancera, David Veesler. 2018. Germline VRC01 antibody identification of the improved clade C HIV-1 envelope trimer, 2 Fabs destined, sharpened map. EMBL-EBI Proteins Data Loan provider. EMD-9303Andrew J. Borst, Connor E. Weidle, Matthew D. Grey, Brandon Frenz, Joost Snijder, M. Gordon Joyce, Ivelin S. Georgiev, Guillaume B.E. Stewart-Jones, Peter D. Kwong, Andrew T. McGuire, Frank DiMaio, Leonidas Stamatatos, Marie Pancera, David Veesler. 2018. Germline VRC01 antibody identification of the improved clade C HIV-1 envelope trimer, 3 Fabs destined, sharpened map. RCSB Proteins Data Loan provider. 6MYYAndrew J Borst, Connor E Weidle, Matthew D Grey, Brandon Frenz, Joost Snijder, M Gordon Joyce, Ivelin S Georgiev, Guillaume End up being Stewart-Jones, Peter D Kwong, Andrew T McGuire, Frank DiMaio, Leonidas Stamatatos, Marie Pancera, David Veesler. 2018. Germline VRC01 antibody identification of the improved clade C HIV-1 envelope trimer, 3 Fabs destined, unsharpened map. EMBL-EBI Proteins Data Loan provider. EMD-9294Andrew J. Borst, Connor E. Weidle, Matthew D. Grey, Brandon Frenz, Joost Snijder, M. Gordon Joyce, Ivelin S. Georgiev, Guillaume B.E. Stewart-Jones, Peter D. Kwong, Andrew T. McGuire, Frank DiMaio, Leonidas Stamatatos, Marie Pancera, David Veesler. 2018. Recombinant HIV-1 426c Env Tryptic Break down Glycan Semi-Quantification and Identifications. EBI Satisfaction. PXD011494Andrew J Borst, Connor E Weidle, Matthew D Grey, Brandon Frenz, Joost Snijder, M Gordon Joyce, Ivelin S Georgiev, Guillaume End up being Stewart-Jones, Peter D Kwong, Andrew T McGuire, Frank DiMaio, Leonidas Stamatatos, Marie Pancera, David Veesler. 2018. Crystal framework of glycosylated 426c HIV-1 gp120 primary G459C in complicated with glVRC01 A60C large chain. RCSB Proteins Data Loan provider. 6MFTSupplementary MaterialsSupplementary document 1: BLI kinetics variables of varied 426c primary constructs portrayed using HEK293F cells. elife-37688-supp1.docx (13K) DOI:?10.7554/eLife.37688.020 Supplementary file 2: RMSD Desk looking at unliganded and liganded VRC01GL CDRL1 loop conformations. elife-37688-supp2.docx (13K) DOI:?10.7554/eLife.37688.021 Supplementary file 3: BLI kinetics variables of varied 426c primary constructs expressed using GnTI-/- cells. elife-37688-supp3.docx (13K) DOI:?10.7554/eLife.37688.022 Transparent reporting form. elife-37688-transrepform.pdf (318K) DOI:?10.7554/eLife.37688.023 Data Availability StatementMass spectrometry data have already been deposited towards the Satisfaction archive under accession amount PXD011494. CryoEM maps are for sale to download in the EMDB under accession quantities EMD-9294 (426cDS-SOSIP D3?-VRC01GL, 3 Fabs, sharpened), EMD-9295 (426cDS-SOSIP D3?-VRC01GL, 3 Fabs, unsharpened), EMD-9304 (426cDS-SOSIP Col4a3 D3?-VRC01GL, 2 fabs, unsharpened), and EMD-9303 (426cDS-SOSIP D3?-VRC01GL, 2 fabs, sharpened). Buildings have been transferred towards Ivachtin the PDB under accession quantities PDB 6MYY (426cDS-SOSIP D3?-VRC01GL, 3 Fabs]), PDB-6MZJ (426cDS-SOSIP D3?-VRC01GL, 2 fabs), and 6MFoot (426c core?-VRC01GL) The next datasets were Ivachtin generated: Andrew J Borst, Connor E Weidle, Matthew D Grey, Brandon Frenz, Joost Snijder, M Gordon Joyce, Ivelin S Georgiev, Guillaume End up being Stewart-Jones, Peter D Kwong, Andrew T McGuire, Frank DiMaio, Leonidas Stamatatos, Marie Pancera, David Veesler. 2018. Germline VRC01 antibody identification of the improved clade C HIV-1 envelope trimer, 3 Fabs destined, sharpened map. EMBL-EBI Proteins Data Loan provider. EMD-9294 Andrew J Borst, Connor E Weidle, Matthew D Grey, Brandon Frenz, Joost Snijder, M Gordon Joyce, Ivelin S Georgiev, Guillaume End up being Stewart-Jones, Peter D Kwong, Andrew T McGuire, Frank DiMaio, Leonidas Stamatatos, Marie Pancera, David Veesler. 2018. Germline VRC01 antibody identification of the improved clade C HIV-1 envelope trimer, 2 Fabs destined, unsharpened map. EMBL-EBI Proteins Data Loan provider. EMD-9304 Andrew J Borst, Connor E Weidle, Matthew D Grey, Brandon Frenz, Joost Snijder, M Gordon Joyce, Ivelin S Georgiev, Guillaume End up Ivachtin being Stewart-Jones, Peter D Kwong, Andrew T McGuire, Frank DiMaio, Leonidas Stamatatos, Marie Pancera, David Veesler. 2018. Germline VRC01 antibody identification of the improved clade C HIV-1 envelope trimer, 2 Fabs destined, sharpened map. RSCB Proteins Data Loan provider. 6MZJ Andrew J Borst, Connor E Weidle, Matthew D Grey, Brandon Frenz, Joost Snijder, M Gordon Joyce, Ivelin S Georgiev, Guillaume End up being Stewart-Jones, Peter D Kwong, Andrew T McGuire, Frank DiMaio, Leonidas Stamatatos, Marie Pancera, David Veesler..